Study reveals origins of a cancer affecting the blood and bone marrow
A new study by the NYU Cancer Institute, an NCI-designated cancer center, sheds light on the origins of myeloid leukemia, a type of blood cancer that affects children and adults. The researchers...
View ArticleStudy reveals need for personalized approach in treatment of AML
A new discovery in mice by researchers at Wake Forest Baptist Medical Center may one day allow doctors to spare some patients with acute myeloid leukemia (AML) from toxic treatments, while also opening...
View ArticleBone marrow transplant survival more than doubles for young high-risk...
Bone marrow transplant survival more than doubled in recent years for young, high-risk leukemia patients treated at St. Jude Children's Research Hospital, with patients who lacked genetically matched...
View ArticleUnconventional hunt for new cancer targets leads to a powerful drug candidate...
Scientists at Cold Spring Harbor Laboratory (CSHL) and five other institutions have used an unconventional approach to cancer drug discovery to identify a new potential treatment for acute myeloid...
View ArticleStem cell mobilization therapy found to be safe for bone marrow donors
According to a study published in Blood, the Journal of the American Society of Hematology (ASH), researchers have reported that administration of granulocyte colony-stimulating factor (G-CSF), a drug...
View ArticleUS drug supplies run short, endangering patients
Monika McBride has acute myeloid leukemia, a life-threatening blood cancer that requires six months of intensive chemotherapy. Three days before her third treatment, however, a nurse called to cancel...
View ArticleClinical importance of leukemia stem cells validated
Cancer scientists have long debated whether all cells within a tumour are equal or whether some cancer cells are more potent - a question that has been highly investigated in experimental models in the...
View ArticleResearchers discover gene defect that predisposes people to leukemia
A new genetic defect that predisposes people to acute myeloid leukemia and myelodysplasia has been discovered. The mutations were found in the GATA2 gene. Among its several regulatory roles, the gene...
View ArticleAging stem cells may explain higher prevalence of leukemia, infections among...
Human stem cells aren't immune to the aging process, according to scientists at the Stanford University School of Medicine. The researchers studied hematopoietic stem cells, which create the cells that...
View ArticleTwo-faced leukemia?
One kind of leukemia sometimes masquerades as another, according to a study published online this week in the Journal of Experimental Medicine.
View ArticleGene mutation signals a high risk of recurrence in some older acute-leukemia...
Older people with acute myeloid leukemia and normal looking chromosomes in their cancer cells have a higher risk of recurrence if they have mutations in a gene called ASXL1, according to a new study by...
View ArticleAML patients have high response rate with vorinostat added to treatment
Adding a drug that activates genes to frontline combination therapy for acute myeloid leukemia resulted in an 85 percent remission rate after initial treatment, researchers at The University of Texas...
View ArticlePrognostic model developed for MDS related to prior cancer therapy
A large-scale analysis of patients whose myelodysplastic syndrome is related to earlier cancer treatment overturns the notion that all of them have a poor prognosis, researchers from The University of...
View ArticleNo higher risk of acute leukaemia in close relatives
(Medical Xpress) -- Parents, siblings and children of patients with the most common form of acute leukemia do not run a higher risk of developing the disease as was once believed, according to a new...
View ArticleFirst comprehensive DNA study of mast cell leukemia uncovers clues that could...
Cancer researchers at Cold Spring Harbor Laboratory (CSHL) have carried out the first comprehensive study of the changes seen in the DNA of a patient with mast cell leukemia (MCL), an extremely...
View ArticleChemotherapy may influence leukemia relapse: research
The chemotherapy drugs required to push a common form of adult leukemia into remission may contribute to DNA damage that can lead to a relapse of the disease in some patients, findings of a new study...
View ArticleResearchers discover new therapeutic target for treatment of acute myeloid...
A study by the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has found new interactions between two molecules involved in acute myeloid leukaemia...
View ArticleComputer model of blood development could speed up search for new leukaemia...
The first comprehensive computer model to simulate the development of blood cells could help in the development of new treatments for leukaemia and lymphoma, say researchers at the University of...
View ArticleCould there be a gleevec for brain cancer?
The drug Gleevec (imatinib mesylate) is well known not only for its effectiveness against chronic myeloid leukemia (CML) and acute lymphoblastic leukemia, but also for the story behinds its...
View ArticleStudy provides insights on enzyme that helps direct the immune response to...
An enzyme known to be important in the body's response to kidney injury exerts its protective effects, in part, by affecting the immune system, according to a study appearing in an upcoming issue of...
View Article
